Targeting serine-glycine-one-carbon metabolism as a vulnerability in cancers

• Główni autorzy: Wei Sun (Autor), Ruochen Liu (Autor), Xinyue Gao (Autor), Zini Lin (Autor), Hongao Tang (Autor), Hongjuan Cui (Autor), Erhu Zhao (Autor)
• Format: Książka
• Wydane: BMC, 2023-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract The serine-glycine-one-carbon (SGOC) metabolic pathway is critical for DNA methylation, histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide biosynthesis. The SGOC pathway is a crucial metabolic network in tumorigenesis, wherein the outputs are required...