Targeting serine-glycine-one-carbon metabolism as a vulnerability in cancers
Abstract The serine-glycine-one-carbon (SGOC) metabolic pathway is critical for DNA methylation, histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide biosynthesis. The SGOC pathway is a crucial metabolic network in tumorigenesis, wherein the outputs are required...
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BMC,
2023-05-01T00:00:00Z.
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