Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium.

• Asıl Yazarlar: Nermina Vejzagić (Yazar), Ulrich Fabien Prodjinotho (Yazar), Nagwa El-Khafif (Yazar), Ruili Huang (Yazar), Anton Simeonov (Yazar), Thomas Spangenberg (Yazar), Clarissa Prazeres da Costa (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2021-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

<h4>Background</h4>Anthelminthic treatment options against schistosomiasis are limited. The current treatment relies almost exclusively on a single drug, praziquantel (PZQ). As a consequence, the development of resistance to PZQ and limited activity of PZQ against earlier development sta...