Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease.

• 主要な著者: Shivali Gupta (著者), Xianxiu Wan (著者), Maria P Zago (著者), Valena C Martinez Sellers (著者), Trevor S Silva (著者), Dadjah Assiah (著者), Monisha Dhiman (著者), Sonia Nuñez (著者), John R Petersen (著者), Juan C Vázquez-Chagoyán (著者), Jose G Estrada-Franco (著者), Nisha Jain Garg (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Chagas disease, caused by Trypanosoma cruzi, is endemic in Latin America and an emerging infectious disease in the US and Europe. We have shown TcG1, TcG2, and TcG4 antigens elicit protective immunity to T. cruzi in mice and dogs. Herein, we investigated antigenicity of the recombinant proteins in h...