Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease.

• मुख्य लेखकों: Shivali Gupta (लेखक), Xianxiu Wan (लेखक), Maria P Zago (लेखक), Valena C Martinez Sellers (लेखक), Trevor S Silva (लेखक), Dadjah Assiah (लेखक), Monisha Dhiman (लेखक), Sonia Nuñez (लेखक), John R Petersen (लेखक), Juan C Vázquez-Chagoyán (लेखक), Jose G Estrada-Franco (लेखक), Nisha Jain Garg (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Chagas disease, caused by Trypanosoma cruzi, is endemic in Latin America and an emerging infectious disease in the US and Europe. We have shown TcG1, TcG2, and TcG4 antigens elicit protective immunity to T. cruzi in mice and dogs. Herein, we investigated antigenicity of the recombinant proteins in h...