Role of Caspase-12 in Amyloid β-Peptide-Induced Toxicity in Organotypic Hippocampal Slices Cultured for Long Periods

• Hauptverfasser: Kumiko Ishige (Verfasst von), Noritaka Takagi (Verfasst von), Toru Imai (Verfasst von), Wolf Dieter Rausch (Verfasst von), Yasuhiro Kosuge (Verfasst von), Tetsuroh Kihara (Verfasst von), Kuniko Kusama-Eguchi (Verfasst von), Hiroko Ikeda (Verfasst von), Alexander Rudolf Cools (Verfasst von), John Lionel Waddington (Verfasst von), Noriaki Koshikawa (Verfasst von), Yoshihisa Ito (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2007-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Amyloid β (Aβ) toxicity has been implicated in cell death in the hippocampus, but its specific mechanisms are poorly understood. In this study, Aβ-induced cell death was investigated in organotypic hippocampal slice cultures (OHCs) that were cultured for various periods in vitro. There were no obvio...