Role of Caspase-12 in Amyloid β-Peptide-Induced Toxicity in Organotypic Hippocampal Slices Cultured for Long Periods

• Auteurs principaux: Kumiko Ishige (Auteur), Noritaka Takagi (Auteur), Toru Imai (Auteur), Wolf Dieter Rausch (Auteur), Yasuhiro Kosuge (Auteur), Tetsuroh Kihara (Auteur), Kuniko Kusama-Eguchi (Auteur), Hiroko Ikeda (Auteur), Alexander Rudolf Cools (Auteur), John Lionel Waddington (Auteur), Noriaki Koshikawa (Auteur), Yoshihisa Ito (Auteur)
• Format: Livre
• Publié: Elsevier, 2007-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Amyloid β (Aβ) toxicity has been implicated in cell death in the hippocampus, but its specific mechanisms are poorly understood. In this study, Aβ-induced cell death was investigated in organotypic hippocampal slice cultures (OHCs) that were cultured for various periods in vitro. There were no obvio...