IL-7 Induces an Epitope Masking of γc Protein in IL-7 Receptor Signaling Complex

• Prif Awduron: Tae Sik Goh (Awdur), Yuna Jo (Awdur), Byunghyuk Lee (Awdur), Geona Kim (Awdur), Hyunju Hwang (Awdur), Eunhee Ko (Awdur), Seung Wan Kang (Awdur), Sae-Ock Oh (Awdur), Sun-Yong Baek (Awdur), Sik Yoon (Awdur), Jung Sub Lee (Awdur), Changwan Hong (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Hindawi Limited, 2017-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

IL-7 signaling via IL-7Rα and common γ-chain (γc) is necessary for the development and homeostasis of T cells. Although the delicate mechanism in which IL-7Rα downregulation allows the homeostasis of T cell with limited IL-7 has been well known, the exact mechanism behind the interaction between IL-...