Characterization of the Burkholderia mallei tonB Mutant and Its Potential as a Backbone Strain for Vaccine Development.

• Asıl Yazarlar: Tiffany M Mott (Yazar), Sudhamathi Vijayakumar (Yazar), Elena Sbrana (Yazar), Janice J Endsley (Yazar), Alfredo G Torres (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

BACKGROUND:In this study, a Burkholderia mallei tonB mutant (TMM001) deficient in iron acquisition was constructed, characterized, and evaluated for its protective properties in acute inhalational infection models of murine glanders and melioidosis. METHODOLOGY/PRINCIPAL FINDINGS:Compared to the wil...