Characterization of the Burkholderia mallei tonB Mutant and Its Potential as a Backbone Strain for Vaccine Development.

BACKGROUND:In this study, a Burkholderia mallei tonB mutant (TMM001) deficient in iron acquisition was constructed, characterized, and evaluated for its protective properties in acute inhalational infection models of murine glanders and melioidosis. METHODOLOGY/PRINCIPAL FINDINGS:Compared to the wil...

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Hoofdauteurs: Tiffany M Mott (Auteur), Sudhamathi Vijayakumar (Auteur), Elena Sbrana (Auteur), Janice J Endsley (Auteur), Alfredo G Torres (Auteur)
Formaat: Boek
Gepubliceerd in: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
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