Epigenetic targets of Janus kinase inhibitors are linked to genetic risks of rheumatoid arthritis

• Prif Awduron: Haruka Tsuchiya (Awdur), Mineto Ota (Awdur), Haruka Takahashi (Awdur), Hiroaki Hatano (Awdur), Megumi Ogawa (Awdur), Sotaro Nakajima (Awdur), Risa Yoshihara (Awdur), Tomohisa Okamura (Awdur), Shuji Sumitomo (Awdur), Keishi Fujio (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: BMC, 2024-06-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Background Current strategies that target cytokines (e.g., tumor necrosis factor (TNF)-α), or signaling molecules (e.g., Janus kinase (JAK)) have advanced the management for allergies and autoimmune diseases. Nevertheless, the molecular mechanism that underpins its clinical efficacy have la...