Quercetin prevents primordial follicle loss via suppression of PI3K/Akt/Foxo3a pathway activation in cyclophosphamide-treated mice

• मुख्य लेखकों: Jianghui Li (लेखक), Hui Long (लेखक), Yanyan Cong (लेखक), Hongyuan Gao (लेखक), Qifeng Lyu (लेखक), Sha Yu (लेखक), Yanping Kuang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Chemotherapy improves the survival rates of patients with various cancers but often causes some adverse effects, including ovarian damage, characterised by a decrease in primordial follicle stockpiles. Recent studies have revealed that chemotherapy may stimulate the PI3K signalli...