Saikosaponin d Alleviates Liver Fibrosis by Negatively Regulating the ROS/NLRP3 Inflammasome Through Activating the ERβ Pathway

Background and aims: Saikosaponin d (SSd) has a steroidal structure and significant anti-inflammatory effects. The purpose of this study was to explore the mechanism underlying SSd's inhibitory effects on liver fibrosis.Methods: Wild-type and estrogen receptor knockout (ERKO) mice were treated...

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Main Authors: Kehui Zhang (Author), Liubing Lin (Author), Yingying Zhu (Author), Na Zhang (Author), Meng'en Zhou (Author), Yong Li (Author)
Format: Book
Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
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