Saikosaponin d Alleviates Liver Fibrosis by Negatively Regulating the ROS/NLRP3 Inflammasome Through Activating the ERβ Pathway

• Váldodahkkit: Kehui Zhang (Dahkki), Liubing Lin (Dahkki), Yingying Zhu (Dahkki), Na Zhang (Dahkki), Meng'en Zhou (Dahkki), Yong Li (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background and aims: Saikosaponin d (SSd) has a steroidal structure and significant anti-inflammatory effects. The purpose of this study was to explore the mechanism underlying SSd's inhibitory effects on liver fibrosis.Methods: Wild-type and estrogen receptor knockout (ERKO) mice were treated...