Saikosaponin d Alleviates Liver Fibrosis by Negatively Regulating the ROS/NLRP3 Inflammasome Through Activating the ERβ Pathway

• Päätekijät: Kehui Zhang (Tekijä), Liubing Lin (Tekijä), Yingying Zhu (Tekijä), Na Zhang (Tekijä), Meng'en Zhou (Tekijä), Yong Li (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background and aims: Saikosaponin d (SSd) has a steroidal structure and significant anti-inflammatory effects. The purpose of this study was to explore the mechanism underlying SSd's inhibitory effects on liver fibrosis.Methods: Wild-type and estrogen receptor knockout (ERKO) mice were treated...