Preparation and evaluation of biological activity of ZSM-5 nanoparticles loaded with gefitinib for the treatment of non-small cell lung carcinoma

• Autori principali: Farah Al-Sahlawi (Autore), Israa Al-Ani (Autore), Mohamed El-Tanani (Autore), Hafiz Aadil Farooq (Autore)
• Natura: Libro
• Pubblicazione: Pensoft Publishers, 2024-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background: Gefitinib (GEF) is a tyrosine kinase inhibitor that has proven good efficacy against Non-small cell Lung Carcinoma (NSCLC). It has low solubility and dissolution rate and low oral bioavailability. This work aimed to improve efficacy by loading on ZSM-5 silica nanoparticles and testing th...