Preparation and evaluation of biological activity of ZSM-5 nanoparticles loaded with gefitinib for the treatment of non-small cell lung carcinoma

• मुख्य लेखकों: Farah Al-Sahlawi (लेखक), Israa Al-Ani (लेखक), Mohamed El-Tanani (लेखक), Hafiz Aadil Farooq (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Pensoft Publishers, 2024-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Gefitinib (GEF) is a tyrosine kinase inhibitor that has proven good efficacy against Non-small cell Lung Carcinoma (NSCLC). It has low solubility and dissolution rate and low oral bioavailability. This work aimed to improve efficacy by loading on ZSM-5 silica nanoparticles and testing th...