SPAK and OSR1 Dependent Down-Regulation of Murine Renal Outer Medullary K+ Channel ROMK1

• Asıl Yazarlar: Bernat Elvira (Yazar), Carlos Munoz (Yazar), Jose Borras (Yazar), Hong Chen (Yazar), Jamshed Warsi (Yazar), Sumant Singh Ajay (Yazar), Ekaterina Shumilina (Yazar), Florian Lang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Karger Publishers, 2014-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background/Aims: The kinases SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1) participate in the regulation of the NaCl cotransporter NCC and the Na+,K+,2Cl- cotransporter NKCC2. The kinases are regulated by WNK (with-no-K[Lys]) kinases. Mutations of ge...