SPAK and OSR1 Dependent Down-Regulation of Murine Renal Outer Medullary K+ Channel ROMK1

• Päätekijät: Bernat Elvira (Tekijä), Carlos Munoz (Tekijä), Jose Borras (Tekijä), Hong Chen (Tekijä), Jamshed Warsi (Tekijä), Sumant Singh Ajay (Tekijä), Ekaterina Shumilina (Tekijä), Florian Lang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Karger Publishers, 2014-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background/Aims: The kinases SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1) participate in the regulation of the NaCl cotransporter NCC and the Na+,K+,2Cl- cotransporter NKCC2. The kinases are regulated by WNK (with-no-K[Lys]) kinases. Mutations of ge...