Nanonization and Deformable Behavior of Fattigated Peptide Drug in Mucoadhesive Buccal Films

• Hoofdauteurs: Woojun Kim (Auteur), Hai V. Ngo (Auteur), Hy D. Nguyen (Auteur), Ji-Min Park (Auteur), Kye Wan Lee (Auteur), Chulhun Park (Auteur), Jun-Bom Park (Auteur), Beom-Jin Lee (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

This study was tasked with the design of mucoadhesive buccal films (MBFs) containing a peptide drug, leuprolide (LEU), or its diverse nanoparticles (NPs), for enhanced membrane permeability via self-assembled nanonization and deformable behavior. An LEU-oleic acid conjugate (LOC) and its self-assemb...