PTHG2 Reduces Bone Loss in Ovariectomized Mice by Directing Bone Marrow Mesenchymal Stem Cell Fate

• Auteurs principaux: Jiao Chen (Auteur), Hao Zhang (Auteur), Xianmin Wu (Auteur), Fuxiao Wang (Auteur), Yili Wang (Auteur), Qianmin Gao (Auteur), Han Liu (Auteur), Yan Hu (Auteur), Jiacan Su (Auteur), Yingying Jing (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2021-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Teriparatide, also known as 1-34 parathyroid hormone (PTH (1-34)), is commonly used for the treatment of osteoporosis in postmenopausal women. But its therapeutic application is restricted by poor metabolic stability, low bioavailability, and rapid clearance. Herein, PTHG2, a glycosylated teriparati...