PTHG2 Reduces Bone Loss in Ovariectomized Mice by Directing Bone Marrow Mesenchymal Stem Cell Fate

• Autors principals: Jiao Chen (Autor), Hao Zhang (Autor), Xianmin Wu (Autor), Fuxiao Wang (Autor), Yili Wang (Autor), Qianmin Gao (Autor), Han Liu (Autor), Yan Hu (Autor), Jiacan Su (Autor), Yingying Jing (Autor)
• Format: Llibre
• Publicat: Hindawi Limited, 2021-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Teriparatide, also known as 1-34 parathyroid hormone (PTH (1-34)), is commonly used for the treatment of osteoporosis in postmenopausal women. But its therapeutic application is restricted by poor metabolic stability, low bioavailability, and rapid clearance. Herein, PTHG2, a glycosylated teriparati...