PTHG2 Reduces Bone Loss in Ovariectomized Mice by Directing Bone Marrow Mesenchymal Stem Cell Fate

• Egile Nagusiak: Jiao Chen (Egilea), Hao Zhang (Egilea), Xianmin Wu (Egilea), Fuxiao Wang (Egilea), Yili Wang (Egilea), Qianmin Gao (Egilea), Han Liu (Egilea), Yan Hu (Egilea), Jiacan Su (Egilea), Yingying Jing (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2021-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Teriparatide, also known as 1-34 parathyroid hormone (PTH (1-34)), is commonly used for the treatment of osteoporosis in postmenopausal women. But its therapeutic application is restricted by poor metabolic stability, low bioavailability, and rapid clearance. Herein, PTHG2, a glycosylated teriparati...