Global transcriptomic analysis of the arcuate nucleus following chronic glucocorticoid treatment

• Hoofdauteurs: Jonathan R. Wray (Auteur), Alison Davies (Auteur), Charlotte Sefton (Auteur), Tiffany-Jayne Allen (Auteur), Antony Adamson (Auteur), Philip Chapman (Auteur), Brian Y.H. Lam (Auteur), Giles S.H. Yeo (Auteur), Anthony P. Coll (Auteur), Erika Harno (Auteur), Anne White (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2019-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: Glucocorticoids (GCs) are widely prescribed medications that are well recognized to cause adverse metabolic effects including hyperphagia, obesity, and hyperglycemia. These effects have been recapitulated in a murine model of GC excess, and we hypothesize that they are mediated, in part,...