Global transcriptomic analysis of the arcuate nucleus following chronic glucocorticoid treatment

• मुख्य लेखकों: Jonathan R. Wray (लेखक), Alison Davies (लेखक), Charlotte Sefton (लेखक), Tiffany-Jayne Allen (लेखक), Antony Adamson (लेखक), Philip Chapman (लेखक), Brian Y.H. Lam (लेखक), Giles S.H. Yeo (लेखक), Anthony P. Coll (लेखक), Erika Harno (लेखक), Anne White (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2019-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: Glucocorticoids (GCs) are widely prescribed medications that are well recognized to cause adverse metabolic effects including hyperphagia, obesity, and hyperglycemia. These effects have been recapitulated in a murine model of GC excess, and we hypothesize that they are mediated, in part,...