Global transcriptomic analysis of the arcuate nucleus following chronic glucocorticoid treatment

• Main Authors: Jonathan R. Wray (Author), Alison Davies (Author), Charlotte Sefton (Author), Tiffany-Jayne Allen (Author), Antony Adamson (Author), Philip Chapman (Author), Brian Y.H. Lam (Author), Giles S.H. Yeo (Author), Anthony P. Coll (Author), Erika Harno (Author), Anne White (Author)
• Format: Book
• Published: Elsevier, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Glucocorticoids (GCs) are widely prescribed medications that are well recognized to cause adverse metabolic effects including hyperphagia, obesity, and hyperglycemia. These effects have been recapitulated in a murine model of GC excess, and we hypothesize that they are mediated, in part,...