Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• Prif Awduron: Maral Mokhtari (Awdur), Farzaneh Mostanbet (Awdur), Saideh Nekooee Fard (Awdur), Golsa Shekarkhar (Awdur), Mozhdeh Sepaskhah (Awdur), Maryam Sadat Sadati (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...