Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• Hauptverfasser: Maral Mokhtari (Verfasst von), Farzaneh Mostanbet (Verfasst von), Saideh Nekooee Fard (Verfasst von), Golsa Shekarkhar (Verfasst von), Mozhdeh Sepaskhah (Verfasst von), Maryam Sadat Sadati (Verfasst von)
• Format: Buch
• Veröffentlicht: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• Schlagworte: article
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Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...