Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• मुख्य लेखकों: Maral Mokhtari (लेखक), Farzaneh Mostanbet (लेखक), Saideh Nekooee Fard (लेखक), Golsa Shekarkhar (लेखक), Mozhdeh Sepaskhah (लेखक), Maryam Sadat Sadati (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...