Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• 主要な著者: Maral Mokhtari (著者), Farzaneh Mostanbet (著者), Saideh Nekooee Fard (著者), Golsa Shekarkhar (著者), Mozhdeh Sepaskhah (著者), Maryam Sadat Sadati (著者)
• フォーマット: 図書
• 出版事項: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...