Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• Үндсэн зохиолчид: Maral Mokhtari (Зохиогч), Farzaneh Mostanbet (Зохиогч), Saideh Nekooee Fard (Зохиогч), Golsa Shekarkhar (Зохиогч), Mozhdeh Sepaskhah (Зохиогч), Maryam Sadat Sadati (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...