Synthesis, Characterization, Bioavailability and Antimicrobial Studies of Cefuroxime-Based Organic Salts and Ionic Liquids

• Auteurs principaux: Francisco Faísca (Auteur), Željko Petrovski (Auteur), Inês Grilo (Auteur), Sofia A. C. Lima (Auteur), Miguel M. Santos (Auteur), Luis C. Branco (Auteur)
• Format: Livre
• Publié: MDPI AG, 2024-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Low oral bioavailability is a common feature in most drugs, including antibiotics, due to low solubility in physiological media and inadequate cell permeability, which may limit their efficacy or restrict their administration in a clinical setting. Cefuroxime is usually administered in its prodrug f...