Synthesis, Characterization, Bioavailability and Antimicrobial Studies of Cefuroxime-Based Organic Salts and Ionic Liquids

• المؤلفون الرئيسيون: Francisco Faísca (مؤلف), Željko Petrovski (مؤلف), Inês Grilo (مؤلف), Sofia A. C. Lima (مؤلف), Miguel M. Santos (مؤلف), Luis C. Branco (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2024-10-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Low oral bioavailability is a common feature in most drugs, including antibiotics, due to low solubility in physiological media and inadequate cell permeability, which may limit their efficacy or restrict their administration in a clinical setting. Cefuroxime is usually administered in its prodrug f...