mRNA-Based Nanomedicinal Products to Address Corneal Inflammation by Interleukin-10 Supplementation

• Main Authors: Itziar Gómez-Aguado (Author), Julen Rodríguez-Castejón (Author), Marina Beraza-Millor (Author), Mónica Vicente-Pascual (Author), Alicia Rodríguez-Gascón (Author), Sara Garelli (Author), Luigi Battaglia (Author), Ana del Pozo-Rodríguez (Author), María Ángeles Solinís (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The anti-inflammatory cytokine Interleukin-10 (IL-10) is considered an efficient treatment for corneal inflammation, in spite of its short half-life and poor eye bioavailability. In the present work, mRNA-based nanomedicinal products based on solid lipid nanoparticles (SLNs) were developed in order...