mRNA-Based Nanomedicinal Products to Address Corneal Inflammation by Interleukin-10 Supplementation

• Hoofdauteurs: Itziar Gómez-Aguado (Auteur), Julen Rodríguez-Castejón (Auteur), Marina Beraza-Millor (Auteur), Mónica Vicente-Pascual (Auteur), Alicia Rodríguez-Gascón (Auteur), Sara Garelli (Auteur), Luigi Battaglia (Auteur), Ana del Pozo-Rodríguez (Auteur), María Ángeles Solinís (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The anti-inflammatory cytokine Interleukin-10 (IL-10) is considered an efficient treatment for corneal inflammation, in spite of its short half-life and poor eye bioavailability. In the present work, mRNA-based nanomedicinal products based on solid lipid nanoparticles (SLNs) were developed in order...