Pharmacokinetic Parameters of Quinine in Healthy Subjects and in Patients with Uncomplicated Malaria in Nigeria: Analysis of Data using a Population Approach

• Asıl Yazarlar: Ayorinde Adehin, PhD (Yazar), Sharon I. Igbinoba, PhD (Yazar), Julius O. Soyinka, PhD (Yazar), Cyprian O. Onyeji, PhD (Yazar), Chinedum P. Babalola, PhD (Yazar), Oluseye O. Bolaji, PhD (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2019-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

ABSTRACT: Background: The varied disposition of the antimalarial quinine partly explains its poor tolerance and toxicity in humans. Objective: Using a population approach, the disposition of quinine in healthy subjects and patients with acute uncomplicated symptomatic malaria from Nigeria was re-exa...