Pharmacokinetic-pharmacodynamic correlation of imipenem in pediatric burn patients using a bioanalytical liquid chromatographic method

• Asıl Yazarlar: Silvia Regina Cavani Jorge Santos (Yazar), Cristina Sanches-Giraud (Yazar), Carlindo Vieira Silva Júnior (Yazar), David Souza Gomez (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Universidade de São Paulo, 2015-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

<p>A bioanalytical method was developed and applied to quantify the free imipenem concentrations for pharmacokinetics and PK/PD correlation studies of the dose adjustments required to maintain antimicrobial effectiveness in pediatric burn patients. A reverse-phase Supelcosil LC18 column (250 x...