Pharmacokinetic-pharmacodynamic correlation of imipenem in pediatric burn patients using a bioanalytical liquid chromatographic method

<p>A bioanalytical method was developed and applied to quantify the free imipenem concentrations for pharmacokinetics and PK/PD correlation studies of the dose adjustments required to maintain antimicrobial effectiveness in pediatric burn patients. A reverse-phase Supelcosil LC18 column (250 x...

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Main Authors: Silvia Regina Cavani Jorge Santos (Author), Cristina Sanches-Giraud (Author), Carlindo Vieira Silva Júnior (Author), David Souza Gomez (Author)
Format: Book
Published: Universidade de São Paulo, 2015-06-01T00:00:00Z.
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3rd Floor Main Library

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