Pharmacokinetic-pharmacodynamic correlation of imipenem in pediatric burn patients using a bioanalytical liquid chromatographic method

• Hoofdauteurs: Silvia Regina Cavani Jorge Santos (Auteur), Cristina Sanches-Giraud (Auteur), Carlindo Vieira Silva Júnior (Auteur), David Souza Gomez (Auteur)
• Formaat: Boek
• Gepubliceerd in: Universidade de São Paulo, 2015-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<p>A bioanalytical method was developed and applied to quantify the free imipenem concentrations for pharmacokinetics and PK/PD correlation studies of the dose adjustments required to maintain antimicrobial effectiveness in pediatric burn patients. A reverse-phase Supelcosil LC18 column (250 x...