Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris

• Κύριοι συγγραφείς: Saeed Azadi (Συγγραφέας), Seyed Kazem Sadjady (Συγγραφέας), Seyed Alireza Mortazavi (Συγγραφέας), Nasser Naghdi (Συγγραφέας), Arash Mahboubi (Συγγραφέας), Roya Solaimanian (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The methylotrophic yeast Pichia pastoris is a well-established expression host, which is often used in the production of protein pharmaceuticals. This work aimed to evaluate the effect of various concentrations of ascorbic acid in mixed feeding strategy with sorbitol/methanol on productivity of reco...