Methotrexate causes acute hyperplasia of enterochromaffin cells containing substance P in the intestinal mucosa of rats

This study aimed to investigate the acute and chronic effect of methotrexate on the intestinal substance P metabolism after a single administration to rats. Methotrexate caused a significant increase in the number of substance P-containing cells in the ileal mucosa both at 24 and 96 h. Most of enter...

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Main Authors: Takuji Machida (Author), Yuho Takano (Author), Kenji Iizuka (Author), Maiko Machida (Author), Masahiko Hirafuji (Author)
Format: Book
Published: Elsevier, 2017-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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