Dexmedetomidine Attenuates Lipopolysaccharide-Induced Sympathetic Activation and Sepsis via Suppressing Superoxide Signaling in Paraventricular Nucleus

• Asıl Yazarlar: Jin-Hua Bo (Yazar), Jing-Xiao Wang (Yazar), Xiao-Li Wang (Yazar), Yang Jiao (Yazar), Ming Jiang (Yazar), Jun-Liu Chen (Yazar), Wen-Yuan Hao (Yazar), Qi Chen (Yazar), Yue-Hua Li (Yazar), Zheng-Liang Ma (Yazar), Guo-Qing Zhu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Sympathetic overactivity contributes to the pathogenesis of sepsis. The selective α2-adrenergic receptor agonist dexmedetomidine (DEX) is widely used for perioperative sedation and analgesia. We aimed to determine the central roles and mechanisms of DEX in attenuating sympathetic activity and inflam...