Characterization of Non-Specific Uptake and Retention Mechanisms of [¹⁷⁷Lu]Lu-PSMA-617 in the Salivary Glands

• Autori principali: Nathalie Heynickx (Autore), Charlotte Segers (Autore), Amelie Coolkens (Autore), Sarah Baatout (Autore), Koen Vermeulen (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2023-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The radionuclide therapy [¹⁷⁷Lu]Lu-PSMA-617 was recently FDA-approved for treatment of metastatic castration-resistant prostate cancer. Salivary gland toxicity is currently considered as the main dose-limiting side effect. However, its uptake and retention mechanisms in the sa...