Characterization of Non-Specific Uptake and Retention Mechanisms of [¹⁷⁷Lu]Lu-PSMA-617 in the Salivary Glands

• Hoofdauteurs: Nathalie Heynickx (Auteur), Charlotte Segers (Auteur), Amelie Coolkens (Auteur), Sarah Baatout (Auteur), Koen Vermeulen (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The radionuclide therapy [¹⁷⁷Lu]Lu-PSMA-617 was recently FDA-approved for treatment of metastatic castration-resistant prostate cancer. Salivary gland toxicity is currently considered as the main dose-limiting side effect. However, its uptake and retention mechanisms in the sa...