The Synergistic Effect of N2 and N7 Modifications on the Inhibitory Efficacy of mRNA Cap Analogues

• 主要な著者: Karol Kurpiejewski (著者), Karolina Piecyk (著者), Maciej Lukaszewicz (著者), Karol Kamel (著者), Kazimierz Chmurski (著者), Sebastian Kmiecik (著者), Marzena Jankowska-Anyszka (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

In the fight against cancer, researchers have turned their attention to the eukaryotic initiation factor eIF4E, a protein whose increased level is strongly correlated with the development and progression of various types of cancer. Among the numerous strategies devised to tackle eIF4E overexpression...