The Synergistic Effect of N2 and N7 Modifications on the Inhibitory Efficacy of mRNA Cap Analogues

• Hoofdauteurs: Karol Kurpiejewski (Auteur), Karolina Piecyk (Auteur), Maciej Lukaszewicz (Auteur), Karol Kamel (Auteur), Kazimierz Chmurski (Auteur), Sebastian Kmiecik (Auteur), Marzena Jankowska-Anyszka (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

In the fight against cancer, researchers have turned their attention to the eukaryotic initiation factor eIF4E, a protein whose increased level is strongly correlated with the development and progression of various types of cancer. Among the numerous strategies devised to tackle eIF4E overexpression...