The Synergistic Effect of N2 and N7 Modifications on the Inhibitory Efficacy of mRNA Cap Analogues

• Main Authors: Karol Kurpiejewski (Author), Karolina Piecyk (Author), Maciej Lukaszewicz (Author), Karol Kamel (Author), Kazimierz Chmurski (Author), Sebastian Kmiecik (Author), Marzena Jankowska-Anyszka (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the fight against cancer, researchers have turned their attention to the eukaryotic initiation factor eIF4E, a protein whose increased level is strongly correlated with the development and progression of various types of cancer. Among the numerous strategies devised to tackle eIF4E overexpression...