The Synergistic Effect of N2 and N7 Modifications on the Inhibitory Efficacy of mRNA Cap Analogues

• Egile Nagusiak: Karol Kurpiejewski (Egilea), Karolina Piecyk (Egilea), Maciej Lukaszewicz (Egilea), Karol Kamel (Egilea), Kazimierz Chmurski (Egilea), Sebastian Kmiecik (Egilea), Marzena Jankowska-Anyszka (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

In the fight against cancer, researchers have turned their attention to the eukaryotic initiation factor eIF4E, a protein whose increased level is strongly correlated with the development and progression of various types of cancer. Among the numerous strategies devised to tackle eIF4E overexpression...