Paeoniflorin exerts neuroprotective effects by modulating the M1/M2 subset polarization of microglia/macrophages in the hippocampal CA1 region of vascular dementia rats via cannabinoid receptor 2

• 主要な著者: Xian-Qin Luo (著者), Ao Li (著者), Xue Yang (著者), Xiao Xiao (著者), Rong Hu (著者), Tian-Wen Wang (著者), Xiao-Yun Dou (著者), Da-Jian Yang (著者), Zhi Dong (著者)
• フォーマット: 図書
• 出版事項: BMC, 2018-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Cerebral hypoperfusion is a pivotal risk factor for vascular dementia (VD), for which effective therapy remains inadequate. Persistent inflammatory responses and excessive chemotaxis of microglia/macrophages in the brain may accelerate the progression of VD. Endocannabinoids are...