Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory Epilepsy

• Egile Nagusiak: Rui Silva (Egilea), Helena Colom (Egilea), Joana Bicker (Egilea), Anabela Almeida (Egilea), Ana Silva (Egilea), Francisco Sales (Egilea), Isabel Santana (Egilea), Amílcar Falcão (Egilea), Ana Fortuna (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Perampanel is a promising antiepileptic drug (AED) for refractory epilepsy treatment due to its innovative mechanism of action. This study aimed to develop a population pharmacokinetic (PopPK) model to be further used in initial dose optimization of perampanel in patients diagnosed with refractory e...