Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory Epilepsy

• Main Authors: Rui Silva (Author), Helena Colom (Author), Joana Bicker (Author), Anabela Almeida (Author), Ana Silva (Author), Francisco Sales (Author), Isabel Santana (Author), Amílcar Falcão (Author), Ana Fortuna (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Perampanel is a promising antiepileptic drug (AED) for refractory epilepsy treatment due to its innovative mechanism of action. This study aimed to develop a population pharmacokinetic (PopPK) model to be further used in initial dose optimization of perampanel in patients diagnosed with refractory e...