Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory Epilepsy

• Glavni autori: Rui Silva (Autor), Helena Colom (Autor), Joana Bicker (Autor), Anabela Almeida (Autor), Ana Silva (Autor), Francisco Sales (Autor), Isabel Santana (Autor), Amílcar Falcão (Autor), Ana Fortuna (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2023-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Perampanel is a promising antiepileptic drug (AED) for refractory epilepsy treatment due to its innovative mechanism of action. This study aimed to develop a population pharmacokinetic (PopPK) model to be further used in initial dose optimization of perampanel in patients diagnosed with refractory e...