Unravelling the role of Sildenafil and SB204741 in suppressing fibrotic potential of peritoneal fibroblasts obtained from PD patients

• Asıl Yazarlar: Saurabh Chaturvedi (Yazar), Harshit Singh (Yazar), Vikas Agarwal (Yazar), Akhilesh Jaiswal (Yazar), Narayan Prasad (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Introduction: Peritoneal fibrosis (PF) results in technique failure in peritoneal dialysis (PD) patients. Peritoneal fibroblasts are characterized by increase in the ACTA2 gene, responsible for alpha smooth muscle actin (α−SΜΑ), extracellular matrix (ECM) production, and inflammatory cytokines produ...