Unravelling the role of Sildenafil and SB204741 in suppressing fibrotic potential of peritoneal fibroblasts obtained from PD patients

Introduction: Peritoneal fibrosis (PF) results in technique failure in peritoneal dialysis (PD) patients. Peritoneal fibroblasts are characterized by increase in the ACTA2 gene, responsible for alpha smooth muscle actin (α−SΜΑ), extracellular matrix (ECM) production, and inflammatory cytokines produ...

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Main Authors: Saurabh Chaturvedi (Author), Harshit Singh (Author), Vikas Agarwal (Author), Akhilesh Jaiswal (Author), Narayan Prasad (Author)
Format: Book
Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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