From Clinical Trial Efficacy to Real-Life Effectiveness: Why Conventional Metrics do not Work

• প্রধান লেখক: Jean-Pierre Boissel (লেখক), Frédéric Cogny (লেখক), Nicholas Marko (লেখক), François-Henri Boissel (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Adis, Springer Healthcare, 2019-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Randomised, double-blind, clinical trial methodology minimises bias in the measurement of treatment efficacy. However, most phase III trials in non-orphan diseases do not include individuals from the population to whom efficacy findings will be applied in the real world. Thus, a...