From Clinical Trial Efficacy to Real-Life Effectiveness: Why Conventional Metrics do not Work

Abstract Background Randomised, double-blind, clinical trial methodology minimises bias in the measurement of treatment efficacy. However, most phase III trials in non-orphan diseases do not include individuals from the population to whom efficacy findings will be applied in the real world. Thus, a...

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Main Authors: Jean-Pierre Boissel (Author), Frédéric Cogny (Author), Nicholas Marko (Author), François-Henri Boissel (Author)
Format: Book
Published: Adis, Springer Healthcare, 2019-07-01T00:00:00Z.
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