Dwarfism and insulin resistance in male offspring caused by α1-adrenergic antagonism during pregnancy

• Κύριοι συγγραφείς: Rebecca Oelkrug (Συγγραφέας), Beate Herrmann (Συγγραφέας), Cathleen Geissler (Συγγραφέας), Lisbeth Harder (Συγγραφέας), Christiane Koch (Συγγραφέας), Hendrik Lehnert (Συγγραφέας), Henrik Oster (Συγγραφέας), Henriette Kirchner (Συγγραφέας), Jens Mittag (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2017-10-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Objective: Maternal and environmental factors control the epigenetic fetal programming of the embryo, thereby defining the susceptibility for metabolic or endocrine disorders in the offspring. Pharmacological interventions required as a consequence of gestational problems, e.g. hypertension, can pot...