An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer

• मुख्य लेखकों: Huang Tim (लेखक), Nephew Kenneth P (लेखक), Liu Yunlong (लेखक), Li Lang (लेखक), Jeong Jaesik (लेखक), Shen Changyu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2010-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The nuclear transcription factor estrogen receptor alpha (ER-alpha) is the target of several antiestrogen therapeutic agents for breast cancer. However, many ER-alpha positive patients do not respond to these treatments from the begi...