An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer

• Autors principals: Huang Tim (Autor), Nephew Kenneth P (Autor), Liu Yunlong (Autor), Li Lang (Autor), Jeong Jaesik (Autor), Shen Changyu (Autor)
• Format: Llibre
• Publicat: BMC, 2010-11-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The nuclear transcription factor estrogen receptor alpha (ER-alpha) is the target of several antiestrogen therapeutic agents for breast cancer. However, many ER-alpha positive patients do not respond to these treatments from the begi...